Accelerated Brain Gray Matter Loss in Fibromyalgia

Accelerated Brain Loss in Fibromyalgia

This a frightening and devastating discovery, of accelerated brain gray matter loss in Fibromyalgia. It is especially distressing when coupled with the symptoms most fibromyalgia fighters describe as brain fog - not being able to concentrate, not taking information in, poor decision making, poor memory etc. These symtoms are upsetting enough without knowing that our brain is losing it's gray matter.

Gray matter contains most of the brain's neuronal cell bodies. The gray matter includes regions of the brain involved in muscle control, sensory perception such as seeing and hearing, memory, emotions, speech, decision making, and self-control.

This report, published in The Journal of Neuroscience, April 11, 2007, showed there was a decrease in gray matter in fibromyalgia sufferers, relating to how long they'd had the disease. This decrease was much faster than in the normal population.
"The patients, who ranged from 27 to 61 years of age, demonstrated a yearly decrease in gray matter volume more than three times that of age-matched controls."
The research carried out at Universities in both Canada and the UK prove there is Central Nervous System involvement in fibromyalgia.

The question is are these changes in the brain the cause of fibromyalgia or as a consequence of it?

The good news is these findings may mean new approaches in treatment such as protecting the brain and could possibly mean symptoms may be able to be reversed.

Accelerated Brain Gray Matter Loss in Fibromyalgia
MRI of brain.
Does anyone know of any studies that builds on this?

To find out more about the research quoted here please contact M. Catherine Bushnell, McGill Centre for Research on Pain, 3640 University Street, Room M19, Montreal, Quebec, Canada H3A 2B2. Email:



  1. Anonymous4:49 PM

    Please read it is in Spanish but can use google translator. Wrote by Anilein (patient) and approved by Jiri Jerabek, PhD, expert in Fibromialgia.

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  6. This is both frighting and in a way exciting. Knowing that studies are being done to help with the brain fog and other effects of fibromyalgia is exciting but frankly I like my grey matter just the way it is.

    1. Yes Rebecca I so agree with every sentiment. I am still searching for any follow up research on any accelerated brain gray matter loss in Fibromyalgia


Thanks for your input