Duloxetine in Patients With Fibromyalgia

"Early improvements in pain during the first two weeks of treatment with duloxetine were highly predictive of response or nonresponse after three months of treatment, according to the researchers."

What does this mean??

It means there are signs when you first start taking this drug that show if it is going to help your fibro or not. This is from a new study published in the October issue of the Journal of Pain.

Duloxetine, also known as Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela, is a long-acting capsule used to treat depression or generalized anxiety disorder or the pain of diabetic neuropathy or fibromyalgia, or ongoing bone or muscle pain.

Duloxetine is meant to be better than many other medications for the treatment of fibromyalgia as it does not contain as many substances that can cause adverse reactions. Its effectiveness in pain relief is believed to be due to its changing of the nociception system. (pain reception).

Clinical trials have confirmed it gives pain relief, reduces fatigue and improves physical and mental function.

Have you taken this drug and do you agree with this report? Did it help you?


  1. I took Cymbalta for about 8 months and I can't really say it seemed to have any positive effect - unless I was actually meant to be worse during that time LOL... cheers

  2. I LOVED Cymbalta! But when I lost my insurance I did not love the $400 monthly price tag. I am patiently waiting for the generic in 2013, I think. It helped me more than the other 20 some odd drugs I tried so I really hated to lose it.

  3. Learn about acupuncture and other natural treatment options for fibromyalgia. These treatments optimize your sense of well-being without unwanted side effects.

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    1. I found accupuncture for FM to be totally useless and actually increased the if that were possible. So I wouldn't recommend it. Of course everything is worth a try..i it doesn't cost too much.

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  17. Freya4:18 AM

    Thanks for great information I was looking for this information about Cymbalta for my mission to help my pain. I am not ѕure wherе you're getting your info, but good topic. I needs to spend some time learning more or understanding more.

  18. Yes. Cymbalta does help me manage the pain to an extent. Anything is better than nothing.

  19. I guess it helps, but I would like to stop taking it.

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