Cyclobenzaprine for Fibromyalgia
My muscles feel like they are being clenched all the time, especially the muscles in my upper arms, buttocks, thighs and calves. This is a feeling that rarely ever goes away except when I am in warm water at a temperature of 33 to 35 degrees or I am having a massage.

My muscles sometimes go into spasms like cramps and this is especially bad and immobolizing when the larger muscles are involved. One day I stood up but could not move for about 15 minutes due to pain in my buttocks. This has happened 3 times now. It was quite frightening the first time but now I understand what is happening, at least.

 My muscles are in pain, even as I sit here on a comfortable lounge writing this. My wrists and forearms ache from typing and my legs are just in constant pain. I also get restless leg syndrome quite often where my legs are so irritated I cannot get to sleep. The best way I can describe it is that they feel electrified.

I am explaining all this because I have just heard about a medication used in Fibromyalgia for relaxing the muscles called Cyclobenzaprine. It's brand name is Flexeril and I don't understand why it has never been recommended to me by a doctor as it seems to cover these muscle symptoms. As a matter of fact I have never been prescribed any of the muscle relaxants:
  • Cyclobenzaprine (Flexeril)
  • Methocarbamol (Robaxin)
  • Diazepam (Valium)
  • Carisoprodol (Soma)
So on first investigation Cyclobenzaprine gets a good rap:
Cyclobenzaprine has also shown effectiveness in the treatment of fibromyalgia symptoms, with a report of 4.8 patients needing treatment for each (1) patient reporting pain reduction (but no change in fatigue or tender points). Conclusion: Cyclobenzaprine-treated patients were 3 times as likely to report overall improvement and to report moderate reductions in individual symptoms, particularly sleep. Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis
On further investigation many people suffer side effects from Cyclobenzaprine which can range from headache and a tired feeling to dizziness, drowsiness, trouble concentrating, blurred vision, dry mouth or throat, altered sense of taste, nausea, upset stomach and constipation. In elderly patients it can cause confusion, delirium, and cognitive impairment according to the Duke Clinical Research Institute. (PDF)


  1. I did not have any luck with this medication but found a different muscle relaxant that works for me called Zanaflex. It works similarly but is stronger at least for me. It is the ONLY thing that has been able to help me sleep! That alone is worth it!

    1. Me too! And I have tried them all. Thanks for your input.

    2. Anonymous4:53 PM

      Yes, zanaflex is fantastic! Much better than flexaril.

  2. Anonymous12:38 AM

    My Dr explained Flexeril is addictive and with all I have going, I already take some highly addictive meds. I personal found Flex causes drowsiness and leaves me lethargic into the next day! I like Zanaflex but only as needed, not as maintenance. Just my 2 pennies...

  3. Anonymous5:21 PM

    Just to say i use Zanaflex every 12 hours. It helps quite a bit. It doesnt stop the muscle spasms completely but it does help and it is not addictive. Zanaflex plus Elavil to sleep at night is great!

  4. Anonymous4:11 PM

    I also use Flex. Can't say it or any other relaxer I've used helps. I've had more luck with the taking 800 mg of magnesium, just take some time to build up in your system.Good luck to all.

    1. try magnesium maleate!!!! that gets rid of the cramping in legs, feet, hands fingers and toes. the regular magnesium without the maleate did nothing for me. I have been taking it for 8 months now and I tell every Dr I see to tell their other pts. about it and I tell people in my support groups because it really does help.

    2. Anonymous11:36 AM

      I have heard and read a lot about the magnesium going to give it a try after I see my fibromyalgia specialist tomorrow!! I do know that when I soak in Epsom salts with the Magnesium that I do feel quite relaxed and can go to sleep usually

  5. Anonymous6:51 PM

    I took it for neck problems and discovered if I only took 1/2 of one I got relief without side effects. If I took a whole one I ran the ris of waking up with my neck locked.

  6. Anonymous11:22 AM

    I have restless legs, Live in South Africa and take PEXOLA 025mg . Works excellent for legs.

  7. Anonymous9:58 PM

    Oh, the long list of meds I am on for fibro. I have been on flexiril for over a year and until I stopped working I am now able to take it as directed, (twice a day) because it makes me super sleepy. I tried getting off most of my meds, and that did not work well. I was under the impression that they did not work well, and now I know that they do work.

    1. Anonymous11:47 AM

      I totally understand 100% what you are saying I've been on Flexeril for over 10 years I've had fibromyalgia for 30 years now went through all that craziness with doctors telling you it's all in your head and so many different meds, my Med protocol now is morphine 30 mg twice a day 15 mg Lortabs every 4 hours Cymbalta two different doses small dose for at night so that it don't keep me up and a large dose for morning so that it does keep me up! Crazy I know and I'm supposed to take 3 flexerils a day but I only take one at bedtime because it causes sleepiness and I'm always in the bed anyways.... I am also on Klonopin two heart medications Glimmer Pride and Insulin twice a day which that has only started in the last two years I was in bed a full year taking farxiga for my type 2 diabetes and thought it was the fibro keeping me down but come to find out I was highly allergic deathly allergic to farxiga and now I have an enlarged heart and fluid around my heart from it so that's why I have heart medicine. I also have to take Chlor trimeton for allergies an aspirin a day and I have to take stool softeners at night and I'm still very constipated from the morphine and Lortab 😢😢 I have been on most of this medicine for over 10 years I want to get off and get my green card and it's going to be a very hard and long process and I'm scared but I know that this man-made synthetic drugs are definitely harming my body more than the disease!!! So I hope I get my green card and I'm looking for all natural remedies but first I have to see what the fibromyalgia specialist found in the 45 blood work test he took I can't wait to find out tomorrow!!! But I completely understand everyone's issues with medicine it does wicked stuff to you God bless everyone!!!

  8. Anonymous8:36 AM

    I have used flexiril for years and get lots of relief from it. I take nightly so I can wake up and get out of bed when needed and I take as needed during the day. Sometimes, I experience drowsiness but not enough to affect my day.

  9. It actually works with the aid of utilizing remaining off nerve driving forces (or ache sensations) which can be despatched to your mind.However, within the equal cyclobenzaprine dosage high can not be considered as the first elegance of remedy. Is applied collectively with relaxation and physical answer for control skeletal muscle occasions, as an instance, torment or harm. cyclobenzaprine dosage high cyclobenzaprine 10 milligrams will likewise be utilized for purposes not ordered in this pharmaceutical guide.You need to now not utilize cyclobenzaprine high at the off threat which you have a thyroid pain, coronary heart rectangular, congestive coronary heart sadness, a heart musicality disorder, or you have got these days proven a few kindness assault.Do at no time in the future make use of #cyclobenzaprine if you have taken a MAO inhibitor within the previous 14 days. Cyclobenzaprine, the mainstream kingdom of the logo call capsules Flexeril and Amrix, side effects for cyclobenzaprine is a muscle relaxer that assuages throb and uneasiness coming about due to strains, sprains, and other muscle mischances.


Thanks for your input